By Timothy R. Hughes
Transcription components are the molecules that the phone makes use of to interpret the genome: they own sequence-specific DNA-binding task, and both at once or ultimately effect the transcription of genes. In combination, transcription elements keep watch over gene expression and genome association, and play a pivotal position in lots of elements of body structure and evolution.
This e-book presents a reference for significant points of transcription issue functionality, encompassing a basic catalogue of identified transcription issue periods, origins and evolution of particular transcription issue kinds, equipment for learning transcription issue binding websites in vitro, in vivo, and in silico, and mechanisms of interplay with chromatin and RNA polymerase.
Read Online or Download A Handbook of Transcription Factors: 52 (Subcellular Biochemistry) PDF
Best molecular biology books
This quantity is the newest in a brand new sequence that experiences, extensive, key parts of biomedical study on the interface of technology and scientific drugs. those are components within which new discoveries in genetics, molecular, and telephone biology aren't simply improving our knowing of the etiology and development of sickness, yet are discovering purposes in drug improvement and the implementation of recent varieties of treatment.
Sheds new mild on intrinsically disordered proteins and peptides, together with their position in neurodegenerative illnesses With the invention of intrinsically disordered proteins and peptides (IDPs), researchers discovered that proteins don't unavoidably undertake a good outlined secondary and tertiary constitution on the way to practice organic services.
The combo of molecular biology, engineering and bioinformatics has revolutionized our realizing of melanoma revealing a good correlation of the molecular features of the first tumor when it comes to gene expression, structural adjustments of the genome, epigenetics and mutations with its propensity to metastasize and to answer treatment.
This publication is a commonly old account of a outstanding and intensely interesting clinical story–the look for the variety of human chromosomes. It covers the techniques and folks, culminating within the cognizance that getting to know the variety of human chromosomes introduced as a lot profit as unraveling the genetic code itself.
Extra resources for A Handbook of Transcription Factors: 52 (Subcellular Biochemistry)
A Handbook of Transcription Factors: 52 (Subcellular Biochemistry) by Timothy R. Hughes